Craig Bellamy's Wales visit Wembley next month for an international friendly that will act as a warm-up for his side's crucial World Cup qualifier against Belgium a few days later.
Experienced midfielder Aaron Ramsey has been named in Bellamy's squad after a recent move to play his club football in Mexico while Leeds United duo Ethan Ampadu and Joe Rodon also return.
As much as Wales will want to get a result against England, Bellamy having purposely looked for testing friendlies for his players whenever there has been a gap in their World Cup schedule, the game against Belgium is key to hopes of winning their qualifying group.
For England, that objective is all but secured and they follow up the Wales game with a visit to Riga that should yield a further three points against a Latvia side who were well-organised and dogged in the reverse game at Wembley but unlikely to pose a huge threat.
Tuchel names his squad on Friday and should have Jude Bellingham, named as England men's player of the year for 2024/25 this week, available to him once again as he looks to build on the impressive victory in Serbia last time out that all but secured qualification for next summer's North American jamboree.
The game against Wales has been designated as the Alzheimer's Society International and players from both sides will walk out with 22 fans living with dementia in a powerful message designed to highlight awareness of the UK's biggest killer.